Introduction
Description: Colchicine is an antimitotic commonly used for doubling chromosomes.
Synonyms: N-[(7S)-5,6,7, 9-Tetrahydro-1,2,3, 10-Tetramethoxy-9- Oxobenzo[A] Heptalen-7-Yl]Acetamide
Solubility |
Water, Upon dissolution this product is light sensitive |
Physical Form |
Solid |
Storage Temp. |
Room Temperature |
other Notes |
Plant Tissue Culture Tested |
UPC / SKU |
C226 |
CAS NUMBER |
64-86-8 |
Formula Weight |
399.44 |
Formula |
C22H25NO6 |
Synonyms |
N-[(7S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide |
Hazardous Type |
Poison |
Special Packaging |
Poison Pack |
Storage Temp. |
Room Temperature |
Tariff Code |
2924.29.6250 |
Risk Info (R) |
28-36/37/38 |
Safety Info (S) |
13-45-36/37/39 |
No information available
C226 Colchicine
Synonym: N-[(7S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide
CAS: 64-86-8
Formula: C22H25NO6
Molecular Wt: 399.44
Properties |
Form: |
Powder |
Appearance: |
Off-white to Yellow |
Application: |
Mutagen |
Solubility: |
Water |
Typical Working Concentration: |
Varies with application, should be determined by end user. |
Storage Temp: |
Room Temperature |
Storage Temp of Stock Solution: |
2-6°C |
Other Notes: |
Plant Tissue Culture Tested |
Application Notes
This product is commonly used to double chromosomes. λmax: 350.5 nm, 243 nm (Merck).
References
Andreu, J. M., & Timasheff, S. N., (1982) Tubulin bound to colchicine forms polymers different from microtubules. Proc. Natl. Acad. Sci. USA, 79, 6753-6756. Arai, T., and Okuyama, T., (1975) Fluorometric assay of tubulin-colchicine complex. Anal. Biochem., 69,443-450. Merck 13, 2496 Wilson, L & Friedkin, M, (1966) The biochemical events of mitosis. I. Synthesis and properties of colchicine labeled with tritium in its acetyl moiety. Biochemistry, 5, 2463-2468.